After escaping the battle against the Poodle Lady in Egypt, the trio of Milkshake, Frylock, and Meatwad find themselves in a dire situation. Frylock, who tragically perished during the ordeal, is miraculously revived with the help of Lincoln. Before being arrested by the CIA, Lincoln manages to send Milkshake and the others back home... Meanwhile, Meatwad's attempts to pick up girls at a concert in New Jersey prove utterly futile. Milkshake, ever the mentor, takes it upon himself to spread sexual education and proudly showcases his beloved Shake Machine. However, when Frylock searches online for information about the Shake Machine, he stumbles upon a horrifying revelation hidden within its design: the Shake Machine is actually an evil device capable of altering human history and triggering a catastrophic future. At the same time, a group of robots aboard a spaceship plots to seize Milkshake's Shake Machine. On their end, Milkshake, Frylock, and Meatwad must obtain the control motherboard to activate the Shake Machine. After triumphing over the robots in a fierce competition, they finally manage to start the machine, which then transforms into a colossal robot powerful enough to destroy the entire city. Thus begins the absurd showdown between Milkshake's crew and the rampaging Shake Machine...