In a future world where robots and humans coexist, imagination knows no bounds. In the postmodern metropolis of Metropolis, a grand ceremony is being held for the completion of a super skyscraper, hailed as the symbol of progress in this era. As Mr. RED, who holds the city's real power, delivers a passionate speech on stage, a young man in black (RED's adopted son, ROCK) openly draws a gun and shoots amidst heavy security, causing an uproar and chaos among the crowd. Witnessing this incident, Japanese detective Shunsaku Ban, along with his nephew Kenichi, begins a city-wide investigation to hunt down the perpetrator. However, it is revealed that ROCK only shot a robot, and the culprit leaves the scene unscathed. This nation is rife with severe social conflicts. Metropolis is structured as a dual-layered city system, consisting of an advanced above-ground section and a decaying underground part. Among the humans living in this city, some benefit from the highly developed world of robots and enjoy the advantages of civilized technology, while others have lost their jobs to robots and struggle to make ends meet. There are also groups demanding that robots be granted the same human rights and freedoms, leading to various disputes and differing opinions. In particular, a terrorist organization called Marduk, which advocates reclaiming human rights from the robot society and restoring human dignity, has even begun destroying every robot they encounter. —In this chaotic and turbulent nation, the situation is described as being on the brink of explosion, teetering on the edge of collapse. Detective Shunsaku Ban and the robot police officer Bero work together to search for clues, eventually locating the hideout of Dr. Laughton. The doctor has become an internationally wanted criminal for conducting research and creating artificial humans using human bodies. However, Laughton is actually under the secret protection of RED, who has ordered him to continue developing a new type of artificial human. The first of these new "humans" bears the exact appearance of RED's deceased daughter, Tima...