In 1939, Professor Bruttenholm, a consultant on supernatural forces, once vanquished the vampire Erzsebet Ondrushko, who maintained her youthful beauty by bathing in the blood of innocent victims. However, in present-day Upper New York, there are those who seek to resurrect this evil power. The professor begins investigating the matter and joins forces with Hellboy and other supernaturally gifted members to devise a plan of resistance...